Linezolid resistance in vancomycin-resistant Enterococcus faecalis and Enterococcus faecium isolates in a Brazilian hospital.
نویسندگان
چکیده
Lara M. de Almeida, Maria Rita E. de Araújo, Marta F. Iwasaki, Andrey G. Sacramento, Darlan Rocha, Leila P. da Silva, Mónica Pavez, Artemir C. de Brito, Laís Carolina S. Ito, Ana C. Gales, Nilton Lincopan, Jorge L. M. Sampaio, Elsa M. Mamizuka Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil; Laboratory of Clinical Microbiology, Hospital Beneficência Portuguesa, São Paulo, Brazil; Laboratory Alerta, Federal University of São Paulo, São Paulo, Brazil; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil
منابع مشابه
Nosocomial superinfections due to linezolid-resistant Enterococcus faecalis: evidence for a gene dosage effect on linezolid MICs.
Resistance to linezolid among Enterococcus faecium and Enterococcus faecalis isolates has been reported in patients who receive a prolonged course of the drug. We report two cases of linezolid-resistant Enterococcus faecalis that occurred in patients who previously received linezolid for infections with vancomycin-resistant Enterococcus faecium. Both isolates had the G2576U mutation in the 23S ...
متن کاملVancomycin-resistant enteroccus faecium and enterococcus faecalis isolated from education hospital of iran.
INTRODUCTION Enterococci are opportunistic pathogens which represent one of the leading agents of nosocomial infections, especially urinary tract infections (UTI) in hospitalized patients. The aim of the present study was to determine the resistance pattern and the type of resistance genes in vancomycin-resistant Enterococcus isolated from an educational hospital in Iran. MATERIALS AND METHOD...
متن کاملIntensive care unit dissemination of multiple clones of linezolid-resistant Enterococcus faecalis and Enterococcus faecium.
OBJECTIVES Outbreaks caused by linezolid-resistant (LR) enterococci remain rare. We report the epidemiological and molecular characteristics of the multiclonal dissemination of LR enterococci in the intensive care unit (ICU) of a Greek hospital. METHODS All LR enterococcal isolates recovered from patients hospitalized in the ICU of the University Hospital of Larissa, Greece, between January 2...
متن کاملResistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci.
To assess the potential for emergence of resistance during the use of linezolid, we tested 10 clinical isolates of vancomycin-resistant enterococci (VRE) (four Enterococcus faecalis, five Enterococcus faecium, and one Enterococcus gallinarum) as well as a vancomycin-susceptible control (ATCC 29212) strain of E. faecalis. The enterococci were exposed to doubling dilutions of linezolid for 12 pas...
متن کاملبررسی میزان پراکندگی و الگوی مقاومت آنتی بیوتیکی سویه های انتروکوک جدا شده از نمونه های بالینی بیمارستان های آموزشی شهر همدان
Background and purpose: Multi-resistant enterococci are important nosocomial pathogens that are shown to have high prevalence in recent years. Knowledge of antimicrobial resistance pattern is essential to formulate treatment guidelines for infections caused by enterococci. The aim of this study was to investigate the antimicrobial resistance among enterococci isolated from Hamedan hospitals. M...
متن کاملNasal and perirectal colonization of vancomycin sensitive and resistant enterococci in patients of paediatrics ICU (PICU) of tertiary health care facilities
BACKGROUND Enterococci normally inhabit the intestinal tract of humans and are also a potential pathogen in causing nosocomial infections. The increase in antibiotic resistance and transfer of antibiotic resistance gene to Staphylococcus aureus (S. aureus) due to co-colonization has increased its importance in research. The aim of the study was to evaluate local epidemiology of nasal and rectal...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 58 5 شماره
صفحات -
تاریخ انتشار 2014